A STUDY OF CLINICAL, BIOCHEMICAL &RADIOLOGICAL CORRELATION IN THE DIAGNOSIS OF PCOS

Abstract

Aims: To evaluate and compare the clinical, biochemical, radiological features in diagnosis of PCOS Methods: The study was observational study at Medical College Hospital, Kolkata from February 2020 to June 2021. Women 15-35years, in Gynae OPD with history of oligo/ amenorrhea and/or features of hyperandrogenism were the study population. The followings were the study tools 1. Outpatient department tickets, 2. Informed Consent Form 3. Clinical examination 4. Relevant laboratory investigation: Blood for Hb, LH, FSH, AMH, TOTAL TESTOSTERONE, TSH, PROLACTIN, FBS, HbA1C. USG 5. Relevant Books and Journals. 6. Computer hardware and software Result: The mean age group and BMI of our study were 24.95yrs & 25.57kg/m2 respectively; 48% of patients were Overweight & 13% of patients were obese. Women who had clinical features of PCOS had high BMI (69.7% of patient). Ovulatory dysfunction was present in 92% of patients; 88% oligomenorrhea, 4% amenorrhea and 8% normal cycle. In our study; features of HA were present in 81% of patients. Association of AMH (ng/ml) with Clinical Features of HA was statistically significant (p<0.0001). Association of Total Testosterone level with Radiological features of PCOS was statistically significant (p=0.0496). Association between Features HA with Radiological features of PCOS was statistically significant (p=0.0283). Association of LH: FSH with Radiological features of PCOS was statistically significant (p=0.0268). Conclusion: Most of the PCOS patients can be diagnosed by proper history, thorough clinical examination and Ultrasonography of pelvis.