E-ISSN 2583-7761
 
2025, Vol: 3, Issue: 2
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Case Report 


A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA

Neha Anjum, Harish Chilakala.


Abstract
Peutz-Jeghers Syndrome (PJS) is a rare autosomal dominant disorder characterized by hamartomatous polyps throughout the gastrointestinal tract and distinctive mucocutaneous pigmentation. We present a case of PJS in a 17-year-old male who presented with melena, which led to the discovery of multiple hamartomatous polyps in the small intestine, colon, and stomach. Despite the rarity of this syndrome, prompt recognition of its clinical manifestations, including gastrointestinal bleeding, is crucial for early diagnosis and management. This case underscores the importance of considering PJS in the differential diagnosis of patients presenting with melena, as timely intervention can prevent serious complications such as bowel ischemia and malignant transformation. Additionally, it highlights the significance of comprehensive surveillance and screening protocols for individuals with PJS to detect and manage associated malignancies and gastrointestinal complications effectively.

Key words: Peutz-Jeghers Syndrome, melena, Hamartomatous polyps, Mucocutaneous pigmentations


 
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Pubmed Style

Anjum N, Chilakala H. A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. A-JMRHS . 2024; 2(2): 30-33. doi:10.5455/AJMRHS.1107202300023

Web Style

Anjum N, Chilakala H. A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. https://www.ajmrhs.com/?mno=197328 [Access: August 15, 2025]. doi:10.5455/AJMRHS.1107202300023

AMA (American Medical Association) Style

Anjum N, Chilakala H. A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. A-JMRHS . 2024; 2(2): 30-33. doi:10.5455/AJMRHS.1107202300023


Vancouver/ICMJE Style

Anjum N, Chilakala H. A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. A-JMRHS . (2024), [cited August 15, 2025]; 2(2): 30-33. doi:10.5455/AJMRHS.1107202300023


Harvard Style

Anjum, N. & Chilakala, . H. (2024) A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. A-JMRHS , 2 (2), 30-33. doi:10.5455/AJMRHS.1107202300023


Turabian Style

Anjum, Neha, and Harish Chilakala. 2024. A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. Asian Journal of Medical Research & Health Sciences (A-JMRHS), 2 (2), 30-33. doi:10.5455/AJMRHS.1107202300023


Chicago Style

Anjum, Neha, and Harish Chilakala. "A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 2 (2024), 30-33. doi:10.5455/AJMRHS.1107202300023


MLA (The Modern Language Association) Style

Anjum, Neha, and Harish Chilakala. "A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 2.2 (2024), 30-33. Print. doi:10.5455/AJMRHS.1107202300023


APA (American Psychological Association) Style

Anjum, N. & Chilakala, . H. (2024) A RARE CASE OF PEUTZ-JEGHERS SYNDROME PRESENTING WITH MELENA. Asian Journal of Medical Research & Health Sciences (A-JMRHS), 2 (2), 30-33. doi:10.5455/AJMRHS.1107202300023




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