E-ISSN 2583-7761
 

Original Article
Online Published: 17 Aug 2023
 


PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY

Serkan Mola, Gokay Deniz, Zihni Mert Duman, Muhammed Selim Yasar, Alp Yildirim, Garip Altintas.


Abstract
BACKGROUND: The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are novel parameters that have been associated with inflammation in arterial embolism. This study aimed to evaluate NLR and PLR for the prediction of the prognosis in arterial embolism.

METHODS: 197 patients admitted to the hospital with acute extremity embolism who underwent embolectomy with a Fogarty balloon catheter between February 2019 to March 2022 were included in the study. Receiver Operating Characteristics (ROC) curve analysis was generated for NLR and PLT to predict postoperative mortality and amputation. Patients were divided into two groups according to the NLR cut-off value (Low NLR group; High NLR group). The DeLong test was used to compare the area under the curve (AUC) with each of these parameters.

RESULTS: The mean age of the patients was 67.4 ± 15.9 years. The male population was 114 (57.9%). The median neutrophil/lymphocyte ratio was 5.8 (Q1: 3.3- Q3: 10.4), median platelet /lymphocyte ratio was 193.4 (Q1: 128.7- Q3: 298.1). Hospital mortality occurred in 73 patients. ROC curve analysis was performed with NLR to predict hospital mortality. The AUC value was 0.723 (95% CI 0.649 - 0.798, p <0.05). The cut-off for NLR was calculated as 5.97 by predicting hospital mortality (specificity = %66, sensitivity = %70, likelihood ratio: 2.06).

CONCLUSION: High preoperative NLR is an independent mortality predictor for patients who underwent surgical embolectomy. Using NLR as a prognostic indicator for patients undergoing surgical embolectomy will be useful and cost-effective.

Key words: embolism, embolectomy, biomarkers


 
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How to Cite this Article
Pubmed Style

Mola S, Deniz G, Duman ZM, Yasar MS, Yildirim A, Altintas G. PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. A-JMRHS . 2023; 1(2): 42-48. doi:10.5455/AJMRHS.1107202300011


Web Style

Mola S, Deniz G, Duman ZM, Yasar MS, Yildirim A, Altintas G. PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. https://www.ajmrhs.com/?mno=153736 [Access: August 16, 2025]. doi:10.5455/AJMRHS.1107202300011


AMA (American Medical Association) Style

Mola S, Deniz G, Duman ZM, Yasar MS, Yildirim A, Altintas G. PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. A-JMRHS . 2023; 1(2): 42-48. doi:10.5455/AJMRHS.1107202300011



Vancouver/ICMJE Style

Mola S, Deniz G, Duman ZM, Yasar MS, Yildirim A, Altintas G. PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. A-JMRHS . (2023), [cited August 16, 2025]; 1(2): 42-48. doi:10.5455/AJMRHS.1107202300011



Harvard Style

Mola, S., Deniz, . G., Duman, . Z. M., Yasar, . M. S., Yildirim, . A. & Altintas, . G. (2023) PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. A-JMRHS , 1 (2), 42-48. doi:10.5455/AJMRHS.1107202300011



Turabian Style

Mola, Serkan, Gokay Deniz, Zihni Mert Duman, Muhammed Selim Yasar, Alp Yildirim, and Garip Altintas. 2023. PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. Asian Journal of Medical Research & Health Sciences (A-JMRHS), 1 (2), 42-48. doi:10.5455/AJMRHS.1107202300011



Chicago Style

Mola, Serkan, Gokay Deniz, Zihni Mert Duman, Muhammed Selim Yasar, Alp Yildirim, and Garip Altintas. "PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 1 (2023), 42-48. doi:10.5455/AJMRHS.1107202300011



MLA (The Modern Language Association) Style

Mola, Serkan, Gokay Deniz, Zihni Mert Duman, Muhammed Selim Yasar, Alp Yildirim, and Garip Altintas. "PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 1.2 (2023), 42-48. Print. doi:10.5455/AJMRHS.1107202300011



APA (American Psychological Association) Style

Mola, S., Deniz, . G., Duman, . Z. M., Yasar, . M. S., Yildirim, . A. & Altintas, . G. (2023) PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PROGNOSIS AFTER EMBOLECTOMY. Asian Journal of Medical Research & Health Sciences (A-JMRHS), 1 (2), 42-48. doi:10.5455/AJMRHS.1107202300011





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